Groundbreaking methodological advance will support the design of innovative new cancer drugs 10 Apr 2024 Scientists have successfully used a new imaging technique to determine the structure and interactions of a protein complex that plays a significant part in the initiation and progression of cancer. Find out more Show/Hide
Detailed structure of understudied cell division ‘nanomachine’ revealed 31 May 2023 Researchers have revealed, at high-resolution, the structure of a human protein complex named SIN3B, which is a ‘nanomachine’ involved in regulating cell division – a fundamental process for life which, if it becomes uncontrolled, can lead to cancer. Find out more Show/Hide
Cell ‘nanobot’ breakthrough shines light on cause of aggressive cancers 10 May 2023 Scientists have uncovered the inner workings of one of the most important and intricate ‘nanobots’ operating within our cells – using cutting-edge microscopy for visualising molecules almost at an atomic level. Their new study published in Nature has unveiled the critical step that switches on the spliceosome – a piece of cellular machinery that enables cells to build complex proteins. Find out more Show/Hide
Researchers discover potential new series of cancer drugs targeting cancer-driving protein BCL6 09 Feb 2023